Leg pain is a common complaint, often dismissed as a normal part of aging, overuse, or fatigue. But for many patients in Buffalo, Williamsville, Cheektowaga, and Orchard Park, persistent or unusual leg pain can be an early sign of more serious conditions such as venous disease, poor circulation, or even blood clots. Knowing when leg pain is more than just an inconvenience is essential for long-term health.

At GLMI, we provide advanced imaging services to help uncover the root cause of leg pain and guide effective treatment. Here are the top warning signs you should never ignore when it comes to your legs.

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1. Persistent Swelling

If your legs, ankles, or feet are consistently swollen, especially at the end of the day, it may indicate poor circulation or venous insufficiency. Swelling can also signal the presence of blood clots or other vascular issues. Imaging tests such as ultrasound can quickly determine whether swelling is related to vein problems.

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2. Visible Varicose or Spider Veins

While many people think of varicose or spider veins as cosmetic, they are often a warning sign of underlying vein disease. These enlarged, twisted veins appear when valves in the veins are no longer functioning properly, allowing blood to pool. Left untreated, varicose veins can progress to more severe complications.

Our vein and venous disease services are designed to diagnose and manage these conditions effectively before they worsen.

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3. Heaviness or Aching in the Legs

Leg pain that feels like heaviness, throbbing, or dull aching after long periods of standing or sitting is a hallmark sign of venous insufficiency. Many patients notice improvement when they elevate their legs, which is a strong indicator that circulation is involved.

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4. Skin Changes Around the Ankles or Calves

Pay close attention to skin changes on your lower legs. Discoloration, dryness, itching, or thinning of the skin can all indicate poor circulation. In advanced cases, untreated venous disease can cause ulcers or open sores, which are difficult to heal without intervention.

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5. Cramping, Tingling, or Restless Legs

Nighttime cramps, tingling sensations, or the constant urge to move your legs may be linked to circulation problems. While restless leg syndrome can have multiple causes, vein disease is often an overlooked factor. A simple ultrasound exam can help determine if poor blood flow is the culprit.

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6. Sharp Pain or Warmth in One Leg

If one leg suddenly becomes painful, swollen, or warm to the touch, it could indicate deep vein thrombosis (DVT) — a dangerous blood clot. DVT requires immediate medical attention because clots can travel to the lungs and cause life-threatening complications.

GLMI provides advanced imaging and interventional radiology services to diagnose and manage vascular emergencies with precision and care.

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7. Difficulty Walking or Exercise Intolerance

Leg pain that occurs when walking short distances but improves with rest may indicate peripheral artery disease (PAD). This condition occurs when arteries become narrowed, restricting blood flow to the legs. Left untreated, PAD can lead to severe circulation problems and even limb loss.

Preventive screenings with low-dose CT or PET/CT scans may be recommended for at-risk patients to identify blockages early.

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When to Seek Help for Leg Pain

While occasional muscle soreness is normal after activity, leg pain that is persistent, worsening, or accompanied by other symptoms should not be ignored. Warning signs that require immediate attention include:

• Sudden swelling and warmth in one leg.
• Sharp, unexplained pain that does not improve with rest.
• Skin ulcers, discoloration, or non-healing wounds.
• Visible varicose veins accompanied by swelling or pain.
• Recurring leg cramps that disrupt sleep.

These signs may indicate underlying vascular issues that require professional evaluation and treatment.

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How GLMI Helps Diagnose and Treat Leg Pain

At GLMI, we use advanced diagnostic imaging to uncover the cause of leg pain and guide treatment. Depending on your symptoms, our care team may recommend:

• Ultrasound – to check for clots, vein insufficiency, or circulation problems.
• CT scans – to provide detailed images of vascular structures and surrounding tissues.
• PET/CT imaging – for advanced evaluation of systemic disease.
• Interventional radiology – minimally invasive procedures to treat vein or vascular conditions.

Our specialists also work closely with patients to create personalized treatment plans that may include lifestyle changes, compression therapy, or advanced vein care solutions.

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Why Patients in Western New York Choose GLMI

GLMI is proud to serve patients throughout Buffalo and the surrounding Western New York region. With convenient locations in Williamsville, Cheektowaga, and Orchard Park, we make it easy for patients to access high-quality imaging and vein care services close to home.

Our combination of state-of-the-art technology, experienced radiologists, and patient-centered care makes us a trusted resource for diagnosing and treating leg pain caused by circulation or vein problems.

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Take Control of Your Vein Health

Leg pain should never be ignored — especially when it’s persistent, accompanied by swelling, or linked to visible vein changes. These warning signs often point to underlying circulation issues that require professional attention.

Contact GLMI today to schedule a consultation and diagnostic imaging appointment. With early detection and personalized care, our team can help you find answers and protect your long-term vascular health.

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Medical Disclaimer: This article is for informational purposes only and is not a substitute for professional medical advice. Always consult your physician or qualified healthcare provider about your specific symptoms and treatment options.